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Patient-centred models similarly appreciate the significance of psychosocial and quality-of-life end points, such as fatigue, cognitive function, pain, emotional well-being and treatment-related nausea or neuropathy that are commonly endorsed by patients in explaining their motivation to take supplements (236)

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For instance, pregnant women are advised against consuming kombucha due to its ethanol content, substantial acetic acid concentration, and potential presence of substances like heparin (Martínez-Leal et al., 2018